Coagulanolide, a withanolide from Withania coagulans Dunal fruits and antihyperglycemic activity
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چکیده
Scientists at Department of Biology, Science and Letters Faculty and Faculty of Arts and Sciences, Yuzuncu Yil University, Van, Turkey designed their study to investigate the protective and antioxidant properties of pomegranate flowers, Punica granatum Linn. (PG) beverage against trichloroacetic acid (TCA)-exposure in rats. The hepatopreventive and antioxidant potential of the plant’s infusion was evaluated by measuring level of serum enzymes, antioxidant defense systems (ADS) and lipid peroxidation content in various organs of rats. Three experimental
منابع مشابه
New withanolide, acyl and menthyl glucosides from fruits of Withania coagulans Dunal.
The fruits of Withania coagulans Dunal (family: Solanaceae) are sweet, sedative, emetic, alterative and diuretic; used to treat asthma, biliousness, strangury, wounds, dyspepsia, flatulent colic, liver complaints and intestinal infections. Phytochemical investigation of the fruits yielded a withanolide tetraglucoside identified as (20S, 22R)-5alpha, 20alpha-diacetoxy-6beta-hydroxy- 1-oxowitha-2...
متن کاملAnalysis of fatty acid composition of Withania coagulans fruits by gas chromatography/mass spectrometry
Background and objectives: Withania coagulans Dunal (Solanaceae) fruits are recommended to treat asthma, dyspepsia, biliousness, flatulent colic, liver complaints, intestinal infections, strangury, wounds and as diuretic, emetic and sedative agent in Indian traditional system of medicine. The objective of this study was to describe the systematic fatty acid composition...
متن کاملEffect of carbon and nitrogen sources on in vitro flower and fruit formation and withanolides production in Withania somnifera (L.) Dunal.
We studied the influence of sucrose and nitrogen concentration on in vitro flowering and fruit setting in elongated shoots of Withania somnifera. BA (1.5 mg/l) and IAA (0.3 mg/l) on MS medium supplemented with 4% sucrose showed 67% of in vitro flower induction frequency, 9 flowers/shoot, 4 fruits/shoot and 11 seeds/fruit in elongated-shoots. Different concentrations of nitrogen sources (L-gluta...
متن کاملHypolipidemic and antioxidant activity of aqueous extract of fruit of Withania coagulans (Stocks) Dunal in cholesterol-fed hyperlipidemic rabbit model.
Withania coagulans (family: Solanaceae, English: Indian Cheese Maker, Hindi: Doda Paneer) fruit is known for its ethanopharmacological significance in health care system of India. Diet rich in high-fat is an important risk factor for diabetes, atherosclerosis and macro and microvascular complications. Treatment with aqueous extract of fruit of W. coagulans (aqWC; 250 mg/kg body weight) in chole...
متن کاملبررسی فیتوشیمیایی گیاه دارویی و چند منظوره پنیرباد Withania coagulans (Stocks) Dunal در رویشگاه‌های طبیعی استان سیستان و بلوچستان
گیاه پنیرباد (Withania coagulans (Stocks) Dunal)، متعلق به خانواده سولاناسه، ازجمله گیاهان دارویی و چند منظوره است که در ایران، منحصراً در برخی از رویشگاه‌های جنوب‌شرقی استان سیستان و بلوچستان پراکنش دارد. عمده ویژگی دارویی این گیاه مربوط به حضور گروهی از لاکتون‌های استروییدی به نام ویتانولوئیدها می‌باشد. در بین ویتانولیدهای موجود، ترکیب ویتافرین A به دلیل ویژگی بازدارندگی رشد سلول‌ها و تومورهای...
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